Items that activate with low health such as Dark Prince's Crown work well with Eve.

During the period of invincibility after taking damage, the player can spam the Razor Blade quite a few times and vastly increase Eve's damage with no penalty. The Polaroid works very well with the Razor Blade, when Eve is at half-a-Red-Heart or less.Such items include Dark Bum, Book of Revelations, Satanic Bible, Mitre, and many more. As such, items that are conducive to spawning Soul Hearts or Black Hearts will be instrumental for Eve. As Eve will prefer having little to no Red Hearts, she will need alternative ways to stay alive.Following the same logic, items that make deals with the Devil more likely will allow Eve to trade her Red Heart containers away more reliably, making it safer to gain health for the sole purpose of spending it in a Devil Room.Such items include Dead Cat, Guppy's Paw, and Abaddon. Items that take Red Heart containers away typically do so as a cost to counterbalance its potent benefits for Eve, however, this supposed cost will likely be beneficial due to Whore of Babylon.The effect will not occur if the corresponding item is removed or rerolled from Eve's inventory. Birthright: Whore of Babylon is active regardless of health and Dead Bird is active without taking damage.If not already active, be sure to damage yourself upon the Curse Room door before accepting Soul or Black Hearts to activate the Whore of Babylon state. Without any health upgrades, they will lower Eve's health into her Whore of Babylon state, and can potentially hold useful items and/or Soul/Black Hearts to protect Eve after transforming. Curse Rooms are generally useful rooms to find at the beginning of a run.Eve works well when she's low on health using Devil Beggars and Blood Donation Machines are good ways to activate Whore of Babylon.This allows Eve to get to her Whore of Babylon while also granting the damage-up of the Razor Blade, and without lowering the Devil deal chance. Upon donating 439 coins to the Greed Donation Machine, Eve will start with the Razor Blade.However, the use of Pyromaniac does count. When unlocking Eve, gaining Red Heart containers or using Yum Heart does not count as picking up heart pickups.Eve has a 16.25% chance instead of the usual 10% for any nonspecific Heart drop to turn into a Soul Heart.Additionally, Eve's 0.75x damage multiplier will change to 1.00x as long as Whore of Babylon is active. Unlike other characters, Eve's Whore of Babylon's effect activates with one remaining Red Heart, instead of half a heart.

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